Paragraph 1. Introduction

Currently, research is underway in the United States to study the efficacy and safety of the drug tadalafil for the treatment of erectile dysfunction. Tadalafil is a selective phosphodiesterase 5 inhibitor (PDE-5) that increases blood flow to the penis, which promotes erection.

Paragraph 2. Efficiency

According to the results of a study published in the Journal of Sexual Medicine, tadalafil is effective in the treatment of erectile dysfunction of various etiologies. 169 men aged 18 to 65 years participated in the study. The participants were divided into two groups: the first group took tadalafil at a dosage of 20 mg, the second — placebo. As a result, it was found that tadalafil significantly improved erectile function in men with erectile dysfunction of various etiologies.

Paragraph 3. Security

The study, the results of which were published in The journal of Urology, examined the safety of tadalafil in patients with erectile dysfunction and concomitant diseases. The study involved 150 men aged 18 to 75 years. The participants were divided into two groups: the first group took tadalafil at a dosage of 20 mg, the second — placebo. As a result, it was found that tadalafil is well tolerated by patients with erectile dysfunction and concomitant diseases such as hypertension, coronary heart disease, diabetes mellitus and others.

Paragraph 4. Contraindications

Despite the effectiveness and safety, the use of tadalafil has a number of contraindications. The drug should not be taken in the presence of the following conditions:

*  hypersensitivity to tadalafil or any other component of the drug;
*  simultaneous administration with nitrates and other drugs that can cause a decrease in blood pressure;
*  severe renal or hepatic insufficiency;
*  diseases that can lead to priapism (Peyronie's disease, sickle cell anemia, myeloma, and others).

Paragraph 5. Conclusion

Tadalafil is an effective and safe drug for the treatment of erectile dysfunction. However, before taking the drug, it is necessary to consult a doctor. The doctor will conduct an examination, determine the cause of erectile dysfunction and select the optimal dosage of the drug.

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